Search results for "SNP arrays"

showing 2 items of 2 documents

The genetic heritage of Alpine local cattle breeds using genomic SNP data

2020

Abstract Background Assessment of genetic diversity and population structure provides important control metrics to avoid genetic erosion, inbreeding depression and crossbreeding between exotic and locally-adapted cattle breeds since these events can have deleterious consequences and eventually lead to extinction. Historically, the Alpine Arc represents an important pocket of cattle biodiversity with a large number of autochthonous breeds that provide a fundamental source of income for the entire regional economy. By using genotype data from medium-density single nucleotide polymorphism (SNP) arrays, we performed a genome-wide comparative study of 23 cattle populations from the Alpine Arc an…

breedsgenomic SNP dataGenotypelcsh:QH426-470[SDV]Life Sciences [q-bio]BiodiversityEndangered speciesBiologyCrossbreedPolymorphism Single NucleotideGenetic diversityGene flowEvolution MolecularSettore AGR/17 - Zootecnica Generale E Miglioramento Genetico03 medical and health sciencescattle biodiversitycattle biodiversity breeds Italian AlpsGeneticsInbreeding depressionAlpine Cattle breedsAnimalsCattle Breeds genomic SNP data Bovine SNP Alpine Cattle breeds SNP Arrays cattle biodiversityGenetic erosionEcology Evolution Behavior and SystematicsPhylogenybiodiversity030304 developmental biologylcsh:SF1-11002. Zero hunger0303 health sciencesGenetic diversityPhylogenetic tree0402 animal and dairy scienceItalian Alps04 agricultural and veterinary sciencesGeneral Medicine15. Life on landCattle Breeds040201 dairy & animal sciencelcsh:Geneticslocal cattleEvolutionary biologyBovine SNPAnimal Science and ZoologyCattlelcsh:Animal cultureSNP arraySNP ArraysResearch ArticleGenetics Selection Evolution
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Integración de la genómica en la modelización de los tumores neuroblásticos = Integration of genomics in neuroblastic tumors modeling

2015

*Introducción: El neuroblastoma es un tumor maligno embrionario del sistema nervioso simpático con una gran heterogeneidad en la presentación clínica, morfológica y genética y en otras características biológicas. La estratificación de grupos de riesgo pretratamiento se basa en los siguientes factores: edad, estadio, histopatológica del tumor, estado del oncogén MYCN, integridad del brazo cromosómico 11q y ploidía. Por otra parte, los cambios numéricos y estructurales detectados en el perfil genético se han incluido recientemente en la estratificación terapéutica de los pacientes con bajo riesgo a recaer o morir. El amplio espectro clínico de la enfermedad va desde pacientes con neuroblastom…

neuroblastomaSNP arraysFISHMYCN geneintratumoral heterogeneityUNESCO::CIENCIAS MÉDICAS11q deletion:CIENCIAS MÉDICAS [UNESCO]
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